Enabling innovators to build products that create real clinical impact

Apply deep technology expertise to help innovators design, validate, and launch high-impact solutions on time and on budget.

About

At Twenty Seven Labs, we are a boutique consulting firm built by industry veterans from Chronus Health, IBM Research, and leading biotech companies. With decades of proven expertise in microfluidics, biosensors, surface chemistry, and point-of-care diagnostics, we specialize in guiding innovative diagnostic technologies from early feasibility to clinical implementation.

Our team has successfully developed breakthrough platforms, including complete blood count (CBC) and comprehensive metabolic panel (CMP) testing systems, and brings a unique blend of technical depth and commercialization experience. Whether you're a startup building your first prototype or a strategic partner scaling to market, we help bridge the gap between scientific innovation and real-world impact.

Our Expertise

Assay & Diagnostic Development

Complete chemistry and sensor development for lab analyzers and point-of-care diagnostics.

Product & System Engineering

End-to-end design and integration of diagnostic systems and prototypes.

R&D & Technical Strategy

Strategic support across the entire innovation pipeline.

Startups & Investors

Strategic advisory for technical capabilities and partnerships.

Our Offerings

Your Technical Partners from Feasibility to Funding

Assay & Diagnostic Development

  • ELISA, immunoassay, and molecular assay development
  • Surface chemistry, functionalization, and bioconjugation
  • Antibody, peptide, aptamer, oligonucleotide, and enzyme-based assays
  • Point-of-care and lab-based test development
  • Complete Blood Count (CBC) and Comprehensive Metabolic Panel (CMP)
  • SOPs, quality control, interference and stability studies
  • Troubleshooting and training on assay workflows

Product & System Engineering

  • Microfluidics and device integration
  • Electrochemical and optical biosensor development
  • System integration across fluidics, electronics, and analytics
  • Automation and scale-up of lab workflows and devices
  • Calibration system design and quality control loops
  • Lab setup, equipment selection, and instrumentation support

R&D & Technical Strategy

  • Early-stage product ideation and brainstorming
  • Technical data analysis and scientific review
  • Preparing technical presentations for fundraising and due diligence

Startups & Investors

  • Technical diligence for VC and strategic investment
  • Lab infrastructure planning for early-stage companies
  • Training and onboarding for assay development teams

Surface Chemistry

  • Surface modification for immunoassays and molecular assays, lab tests, and protein-protein interactions
  • Protocol development for reagent deposition on silicon, glass, plastics, and microplates
  • Low non-specific binding surface chemistry for downstream diagnostics and research compatibility
  • Feasibility-to-product surface chemistry workflows tailored to scale

Bioconjugation

  • Conjugation of small molecule dyes, oligonucleotides, or enzymes to antibodies
  • Biomolecule conjugation to polystyrene, magnetic, and silica beads
  • Conjugate characterization and purification
  • Scale-up and automation of conjugation processes
  • Customized chemistry development for specific conjugation needs

Our Team

Ashish V. Jagtiani, Ph.D.

Ashish V. Jagtiani, Ph.D.

Deep-tech innovation expert and medical device entrepreneur with 15+ years in diagnostics, biosensing, and microfluidics.

Former Co-founder and CTO of Chronus Health, where he led development of next-generation blood testing platforms and secured $25M+ in funding.

Former IBM Research engineer with multiple patents in biosensor technologies. Expertise in translating early-stage science into clinically impactful medical devices.

Rajinder Bhatia, Ph.D.

Rajinder Bhatia, Ph.D.

Seasoned chemistry and assay development expert with 20+ years in IVD, specializing in immunoassays, infectious diseases, and point-of-care diagnostics.

Former leadership roles at Chronus Health and XIP Diagnostics, directing assay development from feasibility to clinical validation.

Deep expertise in surface chemistry, bioconjugation, and biosensor functionalization. Proven track record building and scaling IVD assays across multiple platforms.

Contact Us

Partner with us on your next R&D project in medical diagnostics.

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